When to screen children with Down syndrome for celiac disease?

نویسندگان

  • Momcilo Pavlovic
  • Nedeljko Radlovic
  • Zoran Lekovic
  • Zorica Stojsic
  • Katja Puleva
  • Karolina Berenji
چکیده

The coexistence of Down syndrome (DS) and celiac disease (CD) has been reported in many studies. In our study, we examined 82 children with DS aged 8 months to 8.6 years for the existence of CD using serological markers immunoglobulin A (IgA) and immunoglobulin G (IgG) transglutaminase antibodies, followed by follow-up determination of total IgA levels. In four children who were positive for one of the above-mentioned antibodies, enteric biopsy has been performed that showed absence of CD. Our findings raise doubt about the need for obligatory serological screening of children with DS aged <8 years.

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عنوان ژورنال:
  • Journal of tropical pediatrics

دوره 56 6  شماره 

صفحات  -

تاریخ انتشار 2010